Harrison’s Internal of Medicine 20th Edition () (PDF) by J. Larry Jameson

Description

The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms

Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible.

Essential for practice and education, the landmark 20th Edition features:

Thoroughly revised content―covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison’s. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care.
State-of-the-art coverage of disease mechanisms: Harrison’s focuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention. Harrison’s summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system’s role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals.
All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals. New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine― Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine.
Important and timely new chapters―such as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and more―offer the very latest, definitive perspectives on must-know topics in medical education and practice.
Updated clinical guidelines, expert opinions, and treatment approaches from renowned editors and authors contribute to the accuracy and immediacy of the text material and present a clear blueprint for optimizing patient outcome.

User’s Reviews

One of the best and the go to resource for Internal Medicine and the 20th edition is only better. The eChapters from the previous edition have been converted to print format which is similar to the format followed prior to the 19th edition. Using sources like Uptodate is great for point of care refresh of knowledge and revision but this is a textbook which will help build a solid foundation of knowledge which is critical to any practicing physician. Before anyone says that it is too voluminous, know that most medical students and residents in India finish this book cover to cover before graduating from residency.

I have read selected portions of Harrison’s 20th. Generally it is very well written and edited. Quite a superb compendium of medical information. However, my four-star rating is based on Chapter 83, Benign and Malignant diseases of the prostate. Approximately 12% of this chapter is devoted to benign prostatic hyperplasia BPH and the remaining 88% to prostate cancer. For Cecil the corresponding numbers are 48% and 52%, respectively, while in CMDT the percentages are 43 and 57. If Harrison’s is intended as a GENERAL internal medicine textbook for medical students or as a reference for GENERAL internists, then it seems that a more expanded coverage of BPH relative to prostate cancer would be useful to them. Of course, editorial decisions must be made to keep this book in two volumes, but I still give it four stars.

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