Microdomains in the Cardiovascular System (2017) (PDF) by Nikolaev, Viacheslav

Description

The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.

Prof. Viacheslav Nikolaev, PhD is the Director of the Institute of Experimental Cardiovascular Research at the University Medical Center Hamburg-Eppendorf, Germany. He is also a member of the German Center for Cardiovascular Research (DZHK). His main interest is live-cell imaging of cardiac cAMP and cGMP microdomains and their role in heart failure.

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