- Year: 1998
- Page Number: 1123
- File Type: PDF
- File Size: 26.37 MB
- Authors/ Editiors: J. Larry Jameson
Debates are taking place in medical schools and on the pages of medical journals about the extent to which medical students need to learn about molecular medicine and about how the subject should be taught. Indeed, the rapid proliferation of modern molecular and genetic techniques and advances in structural biology have made an enormous contribution to our understanding of biologic processes and the mechanisms of disease. Advances in human genetics, immunology, virology, hematology, neurology, drug design, and gene therapy, along with knowledge and applications generated by the Human Genome Project, are converging to create the new interdisciplinary field known as molecular medicine.
Molecular medicine promises to transform medical practice by providing new and more efficient approaches to the diagnosis, prevention, and treatment of a wide spectrum of congenital and acquired disorders. We are already seeing the first fruits of these efforts: several recombinant proteins are on the market, some gene-therapy protocols are undergoing phase 3 clinical trials, and a number of molecular diagnostic kits are now available commercially. Because molecular medicine has already started to become an integral part of medical practice, there is a growing need to integrate it into the medical school curriculum and medical education in general. Principles of Molecular Medicine is well suited to serving this purpose, dealing with the more recent molecular and genetic advances in each major branch of medicine and closing the gap between basic science and the bedside.
The book is organized according to organ systems and comprises more than 120 chapters, each written by outstanding specialists. It opens with a series of chapters that introduce the seminal molecular and cellular concepts of modern biology and genetics — the fundamental principles underlying the organization of the human genome, the transcriptional control of gene expression, and the transmission of human genetic diseases. Other chapters describe the tools and techniques available to characterize genes and mutations and to analyze both their expression and their molecular and cellular pathology. The various facets of human hereditary disorders, including genetic counseling and molecular diagnostic testing, are clearly and comprehensively presented.
“The selection of topics, the ability of the contributors to present complex topics in a clear, concise manner, and the format should all contribute to making this book the standard text and reference in its field. It should be in the collection of every medical library and on the bookshelf of every physician interested in keeping up with the transformation of medicine by molecular genetics.” 5 Stars-Doody’s Health Science Book Review Journal.
“…a first-class reference textbook. The format of this book is easy to follow and is relevant to the way in which medicine is currently practiced. Its division into the traditional disciplines of medicine makes it easy to identify how molecular developments have enhanced our medical knowledge, diagnostic potentials and therapeutic options…The editor-in-chief, his section editors and the contributing authors should all be congratulated on a superb job.”-Molecular Medicine Today
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Principles of Molecular Medicine PDF Free Download
Download Principles of Molecular Medicine 1998 PDF Free
Principles of Molecular Medicine 1998 PDF Free Download
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