Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants (2018) (PDF) by Yvonne Will

Description

A major public health concern, despite regulatory vigilance, is untoward toxicity and other pharmaceutical side effects. This toxicity is often idiosyncratic, and usually not discovered until after a large population has been exposed and injured. Recent laboratory evaluations show that many of these drugs impact mitochondrial function. The realization that mitochondrial toxicity is a widespread and important issue in drug toxicity is increasingly appreciated, and most pharmaceutical companies now either have the technology to assess this risk themselves, or do so via contract research organizations.

Developed as a one-stop reference source for drug safety and toxicology professionals, the second edition of Drug and Environmental Induced Mitochondrial Dysfunction explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. It allows readers to understand the basis of mitochondrial function and the preclinical assessments used and what they reveal about drug effects. The focus is on how the requisite technology continues to evolve and the recent emergence of clinical techniques capable of detecting drug-induced mitochondrial toxicity in patients.

User’s Reviews

Drug and Environmental Induced Mitochondrial Dysfunction provides ample reminders of the intimate connections between mitochondria, pharmacology, and toxicology. The book takes a rather systematic approach to mitochondrial pharmacology and toxicology and, for this reason, will be of use to even those outside of strict drug discovery.

Keywords

Free Download Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants in PDF format
Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants PDF Free Download
Download Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants 2018 PDF Free
Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants 2018 PDF Free Download
Download Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants PDF
Free Download Ebook Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants