Bioinformatics For Dummies 2nd Edition (2011) (PDF) by Jean-Michel Claverie Ph.D.

Description

Were you always curious about biology but were afraid to sit through long hours of dense reading? Did you like the subject when you were in high school but had other plans after you graduated? Now you can explore the human genome and analyze DNA without ever leaving your desktop! Bioinformatics For Dummies is packed with valuable information that introduces you to this exciting new discipline. This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You’ll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to: Analyze all types of sequences Use all types of databases Work with DNA and protein sequences Conduct similarity searches Build a multiple sequence alignment Edit and publish alignments Visualize protein 3-D structures Construct phylogenetic trees This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what’s going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you’ll be searching databases and analyzing sequences like a pro!

User’s Reviews

Editorial Reviews: From the Inside Flap Search databases and analyze sequences like a proGet the most out of your PC and the Web with the right toolsExplore the human genome and analyze DNA — without leaving your desktop! All it takes is the basics of molecular biology and the wealth of information in this friendly guide. You’ll discover the online tools and useful tips you need to ask the right questions, analyze sequences, and compare results. It’s a plain-English introduction to the field!Discover how toDo biological research onlineUse gene-centric databasesVisualize proteins in 3-DInterpret and analyze sequencesProduce and publish results –This text refers to the paperback edition. From the Back Cover Search databases and analyze sequences like a proGet the most out of your PC and the Web with the right toolsExplore the human genome and analyze DNA — without leaving your desktop! All it takes is the basics of molecular biology and the wealth of information in this friendly guide. You’ll discover the online tools and useful tips you need to ask the right questions, analyze sequences, and compare results. It’s a plain-English introduction to the field!Discover how toDo biological research onlineUse gene-centric databasesVisualize proteins in 3-DInterpret and analyze sequencesProduce and publish results –This text refers to the paperback edition. About the Author Jean-Michel Claverie is Professor of Medical Bioinformatics at the School of Medicine of the Université de la Méditerranée, and a consultant in genomics and bioinformatics. He is the founder and current head of the Structural & Genomic Information Laboratory, located in Marseilles, a sunny city on the Mediterranean coast of France. Using science as a pretext to travel, Jean-Michel has held positions in Paris (France), Sherbrooke (PQ, Canada), the Salk Institute (La Jolla, CA), the Pasteur Institute (Paris), Incyte pharmaceutical (Palo Alto, CA); and the National Center for Biotechnology Information (Bethesda, MD). He has used computers in biology since the early days –– his Ph.D. work involved modeling biochemical reactions by programming an 8K Honeywell 516 computer right from the console switches! Although he has no clear recollection of it, he has been credited with introducing the French word “bioinformatique” in the late eighties, before involuntarily coining the catchy “bioinformatics” by mistranslating it while giving a talk in English! Jean-Michel’s current research interests are in microbial and structural genomics, and in the development of bioinformatic methods for the prediction of gene function. He is the author or coauthor of more than 150 scientific publications, and a member of numerous international review panels and scientific councils. In his spare time, he enjoys the relaxed pace of life in Marseilles, with his wife Chantal and their two sons, Nicholas and Raphael. Cedric Notredame is a researcher at the French National Centre for Scientific Research. Cedric has used and abused the facilities offered by science to wander around Europe. After a Ph.D. at EMBL (Heidelberg, Germany) and at the European Bioinformatics Institute (Cambridge, UK) under the supervision of Des Higgins (yes, the ClustalW guy), Cedric did a post-doc at the National Institute of Medical Research (London, UK), in the lab of Willie Taylor and under the supervision of Jaap Heringa. He then did a post-doc in Lausanne (Switzerland) with Phillip Bucher, and remained involved with the Swiss Institute of Bioinformatics for several years. Having had his share of rain, snow, and wind, Cedric has finally settled in Marseilles, where the sun and the sea are simply warmer than any other place he has lived in. Cedric dedicates most of his research to the multiple sequence alignment problem and its many applications in biology. His friends claim that his entire life (past, present, future) is somehow stuffed into the T-Coffee multiple-sequence alignment package. When he is not busy dismantling T-Coffee and brewing new sequences, Cedric enjoys life in the company of his wife, Marita. –This text refers to the paperback edition. Review “…buy soon and read fast!…” (Spixiana, July 2004) “…will be of enormous practical assistance to anyone getting to grips with bioinformatics tools in the course of their research…” (Briefings in Bioinformatics, June 2003) –This text refers to an alternate kindle_edition edition. Read more

Reviews from Amazon users which were colected at the time this book was published on the website:

⭐I like this product. It helped me refresh for my oral comprehensives when my committee asked me about the bioinformatics component of my research. Language is very down-to-earth. This would make a good book for high school students or even freshman-level bioinformatic courses. Very basic…like a “Cliff’s Notes” version of bioinformatics, but still a good resource for “dummies” like me that need things explained on a basic level.

⭐I am a couple years into a PhD in bioinformatics, but this is the book I started with. I knew some biology and some computer science, but I still found a lot of the databases, etc. confusing and the field has a decided lack of simplified documentation (though it is getting better).Of course, bioinformatics is a pretty broad topic and no book could possibly cover everything.If you do not know any biology at all you probably should also get a basic text on genetics/molecular biology (or read thema at the NCBI web site books section for free). You don’t need anything in depth to read the dummies book, just at the level of an introductory biology book. Hint: DNA to RNA, RNA to Protein. And you want to know why proteins are similar because proteins with similar amino acid sequences often have similar chemical properties and therefore similar functions, so if you know what one protein does you can guess what a protein like it probably does.:-)And despite the name of the book the authors are REAL bioinformaticists (T-Coffee rocks!)

⭐The content of the book is fine, it is an easy to read beginners introduction to the basic tools of the trade. However, the content is already hopelessly out of date. All online resources referenced in the book have had SIGNIFICANT modifications to their user interface, making the screenshots and detailed step-by-step instructions more confusing than helpful. Not sure there is a practical way around that difficulty. With a bit of understanding how these databases work and what you are actually trying to do you can figure it out.

⭐Incredible information. Big help for a masters student!

⭐As a Phd student in biology, this book offers great reference for bioinformatics in a clear and smooth manner. it explains briefly the concept behind few notions and then shows you how to search, interpret the data you receive. no previous knowledge of bioinformatics is necessary to have this book. the only problem is that several websites either change/close their website or change the application format and it becomes hard to follow the book instructions. however it is a very important tool for researchers.

⭐There is a lot of the book related to giving you details of particular sites to go to — to perform various tasks. And there is details on exactly the screens you will see how you should fill them out. I found a LOT of that information to be dated and incorrect.I found the information about the basic Bioinformatics tasks to be relevant and accurate, but many of the details given were not of much use, due to the reason given above.

⭐The book is from 2007 and it is outdated in the sense that the webpages shown in the book is too different from what you receive from the websites today in 2014. If you are a novice (and you are if you buy this book) there are so many new concepts and and acronyms, that you cannot find what you are looking for, when the layout of the actual webpages has been changed considerably.

⭐I bought this for a class and the guide itself is great if you want a real short introduction to things like multi-sequence alignments and navigating around NCBI but that’s about all. Poor job getting any new bioinformatics person into the realm of programming (especially in Python). I suppose it’s a starting point for anyone who knows nothing about the world of bioinformatics but you will definitely want to buy other guides to complement it.

⭐Like most of the ‘…for Dummies’ series this is presented in a very readable way. Nothing of the basics is skipped over but it’s not at all laboured.Where there is a problem is that this edition dates from 2007. In itself that’s not an issue because even though that’s the Stone Age as far as molecular biology is concerned, the basics don’t change and have to be grasped before you can get up to speed with the latest developments.However, the way the authors get the message across is by guiding the reader through the exact steps to perform on specific websites in order to get particular information, and some of these websites have changed quite radically in more than a decade. For example, Chapter 2 relies heavily on the ExPASy server and works through an example of how to retrieve a set of genomic data. The fact that even the home page of the site is totally different to the way it’s shown in the book, and the search procedure has also changed, makes it very frustrating trying to work out how to get hold of the necessary data to carry on to the next step.So for explanation of background basics this is fine, but for the practicalities of how to use the various tools then either Youtube videos or Futurelearn/Coursera courses on Bioinformatics specifics are probably more useful.

⭐Good source to understand bioinformatics QUICKLY!

⭐brilliant book

⭐Bought for first time bioinformatics user. Answered the questions I had and some I hadn’t thought of. Good index allows you to jump to areas of relevance.

⭐Letto in parte direi che e’ molto buono. I vari siti web elencati sono cambiati nel frattempo quindi bisogna fare attenzione pero’ l’impianto rimane buono.

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