Ebook Info
- Published:
- Number of pages:
- Format: PDF
- File Size: 14.16 MB
- Authors: Karen Duderstadt
Description
Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5Ξ±-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.
Reviews
The book by Mydlo and Godec is an exceptionally good text for practicing urologists and residents to get an understanding of the current understanding of this disease, prostate cancer (PCa). PCa is a complex disorder, and is unlike many other cancers. On the one hand almost all PCas are indolent, namely the patient will most likely dies of something else, but the small percent that have an aggressive form die very rapidly. The primary tool for detection has been the PSA tests which were virulently attacked by the USPTF.
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