Antibiotic strategies for neonatal sepsis – Navigating efficacy and emerging resistance patterns (2025) Pankaj Soni

Description

A systematic review and meta-analysis evaluating the effectiveness of different antibiotic treatments on neonatal sepsis and analyzing emerging resistance patterns. The study highlights that overall mortality rates associated with neonatal sepsis range from 10 to 30%, with grave concern regarding resistance to aminoglycosides (20-45%) and third-generation cephalosporins (15-35%). It underscores the vital role of antibiotic stewardship programs and local surveillance in tailoring empirical treatment.