Non-adrenergic vasopressors for vasodilatory shock or perioperative vasoplegia – A meta-analysis of randomized controlled trials (2024) Yuki Kotani

Description

A systematic review and meta-analysis of randomized controlled trials (RCTs) evaluating the efficacy of non-adrenergic vasopressors (such as vasopressin, terlipressin, angiotensin II, and methylene blue) in adult patients with vasodilatory shock or perioperative vasoplegia. The study found that the administration of non-adrenergic vasopressors was significantly associated with reduced mortality in patients with septic shock, but effects in cardiac and non-cardiac surgery patients did not reach statistical significance.