Quest for a genetic biomarker for sickle cell disease priapism rationale, progress and implications (2025) Oluwafolajimi Adesanya

Description

This clinical outlook investigates the lack of a consensus predictive biomarker for priapism associated with sickle cell disease (SCD). While current management focuses on symptomatic treatment, the article argues that identifying genetic biomarkers is crucial for risk stratification, enabling preventative or early therapeutic measures against this common vasculopathic complication that often leads to severe erectile dysfunction.