Anaphylactic Shock Case Presentation and Emergency Management – Clinical Differentiation, Pathophysiology, and Adrenaline Protocol (2024) Ahmed abdSam

Description

This document provides a clinical analysis of anaphylactic shock, differentiating it from anaphylactoid reactions based on hypotension. It explains the ’empty heart syndrome’ pathophysiology due to massive vasodilation. Key diagnostic features, including respiratory manifestations (wheeze vs. stridor) and cutaneous signs, are discussed. Management guidelines are centered on the immediate administration of adrenaline (0.5 mg IM into the vastus lateralis), emphasizing its priority over all other medications, along with airway control (intubation for edema) and supportive care.