Chronic Leukemias – Chronic Myeloid Leukemia (CML) and Chronic Lymphocytic Leukemia (CLL) Diagnostic Approach and Staging (2024) NA

Description

This material outlines the diagnostic approach for Chronic Myeloid Leukemia (CML) and Chronic Lymphocytic Leukemia (CLL). It covers classic findings (fatigue, hepatosplenomegaly), laboratory workup including CBC interpretation, differential findings (Basophilia, Smudge Cells), bone marrow biopsy stages (Chronic, Accelerated, Blast Phase CML), cytogenetics (Ph+ CML, BCR-ABL1 fusion gene), immunophenotyping (CD markers for CLL), and the RAI staging system for CLL.