Heart–Lungs interactions the basics and clinical implications (2024) Mathieu Jozwiak

Description

This review analyzes the interplay between the cardiovascular and respiratory systems resulting from respiratory-induced changes in intrathoracic and alveolar pressure. It details the resulting hemodynamic consequences (changes in ventricular preload and afterload) in both spontaneously breathing and mechanically ventilated patients. The text also covers complex pathophysiological mechanisms in critical settings (such as ARDS and COPD) and the clinical application of these interactions in predicting fluid responsiveness using dynamic tests like respiratory variations of pulse pressure.