Aminoglycosides-Related Ototoxicity – Mechanisms, Risk Factors, and Prevention in Pediatric Patients (2023) Serena Rivetti

Description

This review analyzes the molecular mechanisms, risk factors (controllable and uncontrollable), and potential otoprotective strategies related to ototoxicity caused by broad-spectrum aminoglycoside antibiotics in pediatric patients. The article emphasizes the severe and irreversible nature of hearing damage in children and the importance of antibiotic stewardship.