Septic Cardiomyopathy – Difficult Definition, Challenging Diagnosis, Unclear Treatment (2025) George E. Zakynthinos

Description

This review discusses Septic Cardiomyopathy (SCM), a poorly defined and often underdiagnosed complication of sepsis involving transient myocardial dysfunction. SCM cannot be attributed to ischemia or pre-existing cardiac disease. The article explores the multifactorial pathogenesis, including inflammatory cytokines and mitochondrial dysfunction, and notes that diagnosis primarily relies on echocardiography.