Biochemical Changes in Cardiopulmonary Bypass in Cardiac Surgery New Insights (2023) Luan Oliveira Ferreira

Description

This review discusses the biochemical changes in the microcirculation and the systemic inflammatory response that patients develop during cardiopulmonary bypass (CPB) in cardiac surgery. It covers how surgical incision, reperfusion injury, and blood contact activate inflammatory pathways, leading to cytokine production and oxidative stress. This inflammatory storm can damage vital organs, particularly the heart, causing postoperative complications.