Assessment of mitochondrial function and its prognostic role in sepsis – A literature review (2024) Wagner Nedel

Description

This review examines the pathophysiological implications of mitochondrial alterations induced by sepsis, which is characterized by a dysregulated systemic inflammatory response leading to organ dysfunction. It discusses how mitochondrial function, accessed in immune cells like monocytes and lymphocytes, can serve as a biomarker for clinical recovery, immunometabolic status, and responsiveness to oxygen and vasopressor therapies in critically ill septic patients.