Renal Mechanisms of Diuretic Resistance in Congestive Heart Failure (2023) Norbert Lameire

Description

This study reviews the renal aspects of diuretic resistance, focusing on treatment with loop diuretics in patients with congestive heart failure (CHF). It discusses the mechanism of action of different classes of diuretics, the pathophysiological causes of resistance (including the concept of compensatory post-diuretic sodium reabsorption), and summarizes combined therapeutic strategies.