Metabolic Dysfunction–Associated Steatotic Liver Disease – Review Article (2024) Giovanni Targher, M.D.

Description

A comprehensive review discussing the evolution of terminology from NAFLD/NASH to Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) and Steatohepatitis (MASH). The article analyzes the global clinical burden of MASLD as a multisystem disease, covering its natural history, pathophysiology, risk stratification, and emphasizing new metabolism-based pharmacotherapies targeting both the liver and coexisting cardiovascular–kidney–metabolic conditions.