Are you looking for concise, practical answers to those questions that are often left unanswered by traditional pediatric sleep disorder references? Are you seeking brief, evidence-based advice for complicated cases or controversial decisions? Curbside Consultation in Pediatric Sleep Disorders:
Review –This text refers to the paperback edition.
Provide continuous, comprehensive care of patients throughout their lifetimes with this evidence-based guide
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A practical, up-to-date guide to the diagnosis, understanding, and treatment of kidney problems and hypertension in adult patients
Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals.A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This textbook, the first of its kind, addresses all aspects of the disorder – from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors, and treatment. About the Author Randy Q. Cron, MD, PhD University of Alabama at Birmingham Professor of Pediatrics and Medicine Birmingham Alabama USA Edward M. Behrens, MD University of Pennsylvania Perelman School of Medicine Perelman School of Medicine Philadelphia Pennsylvania USA
Current Diagnosis and Treatment
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In the last decade, the clinical management of melanoma has become more effective: basic clinical studies, randomized clinical trials, and new drugs have greatly improved the prognosis of patients, both in the initial and in the advanced stage of the disease.
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The only resource dedicated to delivering concise summaries of the most clinically relevant primary care guideline summaries
It remains the worldwide standard in laboratory haematology and no haematologist should be without it! “This is an excellent book for new learners or for experienced practitioners wanting an update/refresher. If you want a basic book covering all aspects of laboratory and clinical hematology, this is the one for you. If you are a student, this is a must have.” -Valerie L. Ng, PhD MD (Alameda County Medical Center/Highland Hospital) Doody’s Score: 94 – 4 Stars!
This book describes important developments and emerging trends in experimental and clinical cancer gene therapy. It reflects the tremendous advances made over recent years with respect to immunogenes, suicide genes and gene correction therapies, as well as in gene suppression and miRNA therapies. Many of the described strategies focus on the generation of more efficient and specific means of attack at known and novel cellular targets associated with tumor development and progression. The book also details parallel improvements in vector design, vector delivery, and therapeutic efficacy. It offers readers a stimulating, broad overview of advances in the field, linking experimental strategies to their clinical applications.
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An ideal resource for written, oral, and recertifying board study, as well as an excellent reference for everyday clinical practice, Current Surgical Therapy, 13th Edition, provides trusted, authoritative advice on today’s best treatment and management options for general surgery. Residents and practitioners alike appreciate the consistent, highly formatted approach to each topic, as well as the practical, hands-on advice on selecting and implementing current surgical approaches from today’s preeminent general surgeons.
Abilash A. Gopal MD Candidate, Class of 2008 Tufts University School of Medicine Boston, MA Alexander E. Ropper, MD Class of 2007 Tufts University School of Medicine Boston, MA Louis A. Tramontozzi, III, MD Class of 2007 Tufts University School of Medicine Boston, MA
This book provides a comprehensive overview of the approach to retroperitoneal sarcomas, rare and challenging tumors requiring highly specialized, multidisciplinary management. Based on an updated review of the literature and drawing on the expertise of respected authors, it analyzes key topics – such as pre-operative work-up and staging, multimodal therapy, multi-organ resection, surgical complications and management of local recurrence and advanced disease – as well as several other debated issues.
Anil K. Sharma is a lecturer at the Delhi Institute of Pharmaceutical Sciences & Research, University of Delhi, India. He has published 25 peer-reviewed papers in the field of pharmaceutical sciences in national and international reputed journals as well as ten book chapters. His research interests include nutraceutical and functional foods, novel drug delivery systems (NDDs), drug delivery, nanotechnology, health science/life science, and biology/cancer biology/neurobiology. He graduated with a degree in pharmacy from the University of Rajasthan, Jaipur, India, and received a Master of Pharmacy (MPharm) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India, with a specialization in pharmaceutics. Raj K. Keservani, MPharm, is a faculty of pharmaceutics at Sagar Institute of Research and Technology-Pharmacy, Bhopal, India. He has more than seven years of academic (teaching) experience from various institutes of India in pharmaceutical education. He has published 30 peer-reviewed papers in the field of pharmaceutical sciences in national and international journals, fifteen book chapters, two co-authored books, and two edited books. He is also active as a reviewer for several international scientific journals. Mr. Keservani graduated with a pharmacy degree from the Department of Pharmacy, Kumaun University, Nainital (UA), India. He received his Master of Pharmacy (MPharm) (specialization in pharmaceutics) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India. His research interests include nutraceutical and functional foods, novel drug delivery systems (NDDS), transdermal drug delivery/ drug delivery, health science, cancer biology, and neurobiology.
The cyclic nucleotides 3′,5′-adenosine monophosphate (cAMP) and 3′,5′-cyclic guanosine monophosphate (cGMP) play important roles in the control of cardiovascular function under physiological and pathological conditions.
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