Cancer: Principles and Practice of Oncology Primer of Molecular Biology in Cancer 3rd Edition (2020) by Vincent T. DeVita Jr. MD PDF

 

Ebook Info

  • Published: 2020
  • Number of pages: 544 pages
  • Format: PDF
  • File Size: 10.56 MB
  • Authors: Vincent T. DeVita Jr. MD

Description

Recent scientific advances have revolutionized cancer research and practice, creating a body of molecular biology information that is important to research scientists and clinical oncologists alike. Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer, 3rd Edition, keeps you up to date with all that’s new in this rapidly changing field. Derived from DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology – widely regarded as the definitive clinical reference in oncology – the third edition of this popular Primer provides a single-volume, highly focused reference on every important frontier in the molecular biology of cancer. Compiles the knowledge and experience of leading scientists and clinicians in the field.Provides separate chapters on each of the 18 most common cancer types, with state-of-the-art information on how molecular biology advances are impacting clinical practice.Includes a thorough chapter on genetic counseling and genetic testing to help you navigate the challenges and ethical dilemmas of cancer genetics.Covers key topics such as Hallmarks of Cancer, Precision Medicine in Oncology, Cancer Immunotherapy, Pharmacogenomics, and many more. Enrich Your Ebook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone.Easily convert to audiobook, powering your content with natural language text-to-speech.

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Oncology

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Denis Burkitt: A Cancer, the Virus, and the Prevention of Man-Made Diseases (Springer Biographies) (2022) by John H. Cummings PDF

 

Ebook Info

  • Published: 2022
  • Number of pages: 437 pages
  • Format: PDF
  • File Size: 14.53 MB
  • Authors: John H. Cummings

Description

This biography of Dr. Denis Parsons Burkitt, after whom the childhood cancer Burkitt’s lymphoma was named, and who was a pioneer of the dietary fiber movement, paints a personal but holistic portrait of both the man and his life’s work. Featuring excerpts from Dr. Burkitt’s personal diaries, spanning seven decades from his boyhood to just before his passing, and extensive family archives, this book invites readers to follow Burkitt’s journey through life and experience his tribulations and successes. Prof. John Cummings was a colleague of Dr. Burkitt and weaves the tale of his life through the lens of family, faith, and science. The journey takes Burkitt from his childhood in Ireland, a country undergoing major social upheaval, through his medical studies in Dublin, to army service in Africa in the midst of WWII and the independence movements that swept the continent in the following years. During his two decades spent in Uganda, working for the Colonial MedicalService, Burkitt made his first major contribution to cancer research – the characterization of Burkitt’s lymphoma and its possible viral cause. Following his return to England in 1966, he turned his attention to the cause of ā€˜Western Diseases’ especially the role of dietary fibre in the prevention of disease and promotion of health. This earned him even wider international recognition and helped to inspire what is a vital field of research today. The book examines Burkitt’s personal views of the world around him, including his experiences as a committed evangelical Christian who had been raised an Irish Protestant, and the challenges, both familial and cultural, that this elicited from and towards him and his scientific work. The lymphoma and later the fibre story propelled Denis into an orbit of worldwide travel, fame and many honours. An engaging speaker but man of great humility, always giving the credit for much of what he did to others, he left a legacy of evidence and ideas for the causes of cancer and prevention of disease from which we all now benefit.

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Editorial Reviews: From the Back Cover This biography of Dr. Denis Parsons Burkitt, after whom the childhood cancer Burkitt’s lymphoma was named, and who was a pioneer of the dietary fiber movement, paints a personal but holistic portrait of both the man and his life’s work. Featuring excerpts from Dr. Burkitt’s personal diaries, spanning seven decades from his boyhood to just before his passing, and extensive family archives, this book invites readers to follow Burkitt’s journey through life and experience his tribulations and successes. Prof. John Cummings was a colleague of Dr. Burkitt and weaves the tale of his life through the lens of family, faith, and science. The journey takes Burkitt from his childhood in Ireland, a country undergoing major social upheaval, through his medical studies in Dublin, to army service in Africa in the midst of WWII and the independence movements that swept the continent in the following years. During his two decades spent in Uganda, working for the Colonial MedicalService, Burkitt made his first major contribution to cancer research – the characterization of Burkitt’s lymphoma and its possible viral cause. Following his return to England in 1966, he turned his attention to the cause of ā€˜Western Diseases’ especially the role of dietary fibre in the prevention of disease and promotion of health. This earned him even wider international recognition and helped to inspire what is a vital field of research today. The book examines Burkitt’s personal views of the world around him, including his experiences as a committed evangelical Christian who had been raised an Irish Protestant, and the challenges, both familial and cultural, that this elicited from and towards him and his scientific work. The lymphoma and later the fibre story propelled Denis into an orbit of worldwide travel, fame and many honours. An engaging speaker but man of great humility, always giving the credit for much of what he did to others, he left a legacy of evidence and ideas for the causes of cancer and prevention of disease from which we all now benefit. About the Author Professor John H. Cummings, OBE, MA, MSc, MB, ChB, PhD (Hon), FRCP (London and Edinburgh), RNutr., is Emeritus Professor of Experimental Gastroenterology, University of Dundee, School of Medicine.

Immunology

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Breast Cancer Radiation Therapy: A Practical Guide for Technical Applications (2022) by Orit Kaidar-Person PDF

 

Ebook Info

  • Published: 2022
  • Number of pages: 971 pages
  • Format: PDF
  • File Size: 25.75 MB
  • Authors: Orit Kaidar-Person

Description

The book provides, in a comprehensive yet concise way, essential information to improve the knowledge and skills of all healthcare providers involved in the treatment of patients with breast cancer. The content does not focus on general information that is widely available via different sources, but on technical aspects – ā€œhands-onā€ daily practices and principles of radiation oncology that are not included in other books. Drawing on information taught in courses at e.g. the ESTRO School, as well as the authors’ broad clinical experience, the respective contributions reflect and share the expertise of leading experts in breast cancer radiation therapy, supported by sound data and evidence. Each chapter includes a short introduction summarizing the evidence in the literature and ā€œpearlsā€ (a short bullet-point summary), and is enriched by tables, figures and illustrations to provide a concise, easy-to-follow and appealing overview.The book, containing also useful electronic supplementary material, will be of interest to a wide range of readers, including radiation oncologists, radiation technicians, medical physicists, and others involved in breast cancer care.

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Radiology

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Core Curriculum for Oncology Nursing 7th Edition (2023) by Oncology Nursing Society PDF

 

Ebook Info

  • Published: 2023
  • Number of pages: 608 pages
  • Format: PDF
  • File Size: 24.82 MB
  • Authors: Oncology Nursing Society

Description

This definitive resource for the specialty of oncology nursing will help you prepare for oncology nursing practice and for OCNĀ® certification! The Core Curriculum for Oncology Nursing, 7th Edition is the definitive resource for the specialty of oncology nursing, developed in collaboration with the Oncology Nursing Society. Organized to follow the OCNĀ® Exam blueprint, this book covers the entire scope of oncology nursing, including screening and the continuum of cancer care, the scientific basis for practice, types of cancer, treatment modalities, palliation of symptoms, and cultural and spiritual care. An overview of each problem includes assessment, management, and expected patient outcomes. Edited by a team of oncology nursing experts led by Jeannine M. Brant and written in a streamlined outline format, the Core Curriculum is the #1 resource for the specialty of oncology nursing, for initial OCNĀ® certification, and for OCNĀ® recertification.This definitive study resource for oncology nursing practice and the OCNĀ® Examination is the only such resource developed in collaboration with and under the editorship of the Oncology Nursing Society.Easy-to-use outline format makes study and review easier; it begins with theory and continues through the steps of the nursing process.Safety Alerts and emphasis on safety highlight safety considerations to reduce errors and promote quality care.Content on cancer treatment and related nursing care includes the mostcurrent and accurate information, preparing you for the OCNĀ® Exam and for enhanced clinical practice.Approximately 60 full-color illustrations and more than 150 summary tables explain complex concepts in oncology nursing, including up-to-date cancer staging information.Coverage of pharmacologic and nonpharmacologic interventions includes both traditional and alternative therapies.NEW! Updated content throughout reflects the 2022 OCNĀ® Examination blueprint, along with the latest national and international guidelines and the most current research evidence.NEW! A Myelofibrosis chapter is added to address this important cancer type, and a Social Determinants of Health and Financial Toxicity chapteraddresses the cost of cancer treatment and financial burden of cancer treatment on patients and families.NEW! COVID-19–related content reflects the impact of the ongoing pandemic, including differential diagnoses for pulmonary symptoms and the impact of delayed cancer diagnosis and treatment.NEW! Updated emphases mirror those of the American Association of Colleges of Nursing 2021 Essentials as well as the recommendations of the 2020-2030 Future of Nursing report.

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Editorial Reviews: Review Prepare for oncology nursing practice and OCNĀ® certification with the definitive resource for the specialty of oncology nursing

Nursing

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Cancer, Complexity, Computation (Emergence, Complexity and Computation, 46) (2022) by Igor Balaz PDF

 

Ebook Info

  • Published: 2022
  • Number of pages: 355 pages
  • Format: PDF
  • File Size: 10.49 MB
  • Authors: Igor Balaz

Description

This book presents unique compendium of groundbreaking ideas where scientists from many different backgrounds are united in their interest in interdisciplinary approaches towards origins and development of cancers, innovative ways of searching for cancer treatment and the role of cancer in the evolution. Chapters give an unequivocal slice of all areas that relate to a quest for understanding cancer and its origin as many-fold nonlinear system, complexity of the cancer developments, a search for cancer treatment using artificial intelligence and evolutionary optimisation, novel modelling techniques, molecular origin of cancer, the role of cancer in evolution of species, interpretation of cancer in terms of artificial life and artificial immune systems, swarm intelligence, cellular automata, computational systems biology, genetic networks, cellular computing, validation through in vitro/vivo tumour models and tumour on chip devices. The book is an inspiring blend of theoretical and experimental results, concepts and paradigms.Distinctive featuresThe book advances widely popular topics of cancer origin, treatment and understanding of its progressThe book is comprised of unique chapters written by world top experts in theoretical and applied oncology, complexity theory, mathematics, computer science.The book illustrates attractive examples of mathematical and computer models and experimental setups.

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Editorial Reviews: From the Back Cover This book presents unique compendium of groundbreaking ideas where scientists from many different backgrounds are united in their interest in interdisciplinary approaches towards origins and development of cancers, innovative ways of searching for cancer treatment and the role of cancer in the evolution. Chapters give an unequivocal slice of all areas that relate to a quest for understanding cancer and its origin as many-fold nonlinear system, complexity of the cancer developments, a search for cancer treatment using artificial intelligence and evolutionary optimisation, novel modelling techniques, molecular origin of cancer, the role of cancer in evolution of species, interpretation of cancer in terms of artificial life and artificial immune systems, swarm intelligence, cellular automata, computational systems biology, genetic networks, cellular computing, validation through in vitro/vivo tumour models and tumour on chip devices. The book is an inspiring blendof theoretical and experimental results, concepts and paradigms.Distinctive featuresThe book advances widely popular topics of cancer origin, treatment and understanding of its progressThe book is comprised of unique chapters written by world top experts in theoretical and applied oncology, complexity theory, mathematics, computer science.The book illustrates attractive examples of mathematical and computer models and experimental setups.

Oncology

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Cancer-Leading Proteases: Structures, Functions, and Inhibition 1st Edition (2020) by Satya Prakash Gupta PDF

 

Ebook Info

  • Published: 2020
  • Number of pages: 935 pages
  • Format: PDF
  • File Size: 7.51 MB
  • Authors: Satya Prakash Gupta

Description

Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases.Explains the role of proteases in the biology of cancerDiscusses how proteases can be used as potential drug targets or as diagnostic and prognostic biomarkersCovers a wide range of cancers and provides detailed discussions on protease examples

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Oncology

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Advanced Skin Cancer: A Case-Based Approach 1st Edition (2022) by Debjani Sahni PDF

 

Ebook Info

  • Published: 2022
  • Number of pages: 174 pages
  • Format: PDF
  • File Size: 23.62 MB
  • Authors: Debjani Sahni

Description

Advanced skin cancer is one that has already metastasized beyond its primary origin, or one that has invaded underlying tissues such that surgical resection either is technically impossible or would lead to an unacceptable functional or cosmetic outcome. These skin cancers present a complex problem that requires the input of multiple specialties to delineate the best management plan. National guidelines utilize the best available data to guide management decisions. However, there is considerable leeway within the guidelines, enabling the ultimate care decision to be molded to best fit each individual patient. This book aims to provide instructional examples of patient cases where the input of the multidisciplinary team is critical in providing the most suitable care plan for the patient.CONTENTS: Melanoma * Squamous Cell Carcinoma * Basal Cell Carcinoma * Cutaneous Lymphoma * Kaposi’s Sarcoma * Dermatofibrosarcoma Protuberans * Merkel Cell Carcinoma * Rare Cancer Presentations

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Editorial Reviews: Review “…provides an understanding of the depth of decision-making involved by multiple specialists in the field”.- Doody’s Review About the Author Senior EditorsDebjani Sahni, MD is a G. Robert Baler Endowed Professor of Dermatology and Director, Cutaneous Oncology Program, Department of Dermatology, Boston University School of MedicineAdam Lerner, MD is Professor of Medicine, Section of Hematology/Oncology, Department of Medicine, Boston University School of MedicineJunior EditorBilal Fawaz, MD is Assistant Professor of Dermatology, Department of Dermatology, Boston University School of Medicine

Dermatology

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Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies (Volume 15) (Cancer Sensitizing Agents for Chemotherapy, Volume 15) 1st Edition (2021) by Ramasamy Paulmurugan PDF

 

Ebook Info

  • Published: 2021
  • Number of pages: 828 pages
  • Format: PDF
  • File Size: 35.45 MB
  • Authors: Ramasamy Paulmurugan

Description

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field.Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistancePresents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistanceDiscusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

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Editorial Reviews: Review Presents the most relevant information on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance From the Back Cover Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are understood comprehensively. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and several members of biomedical field who are interested in understanding the current strategies to fight chemoresistance in glioblastomas. About the Author Dr. Paulmurugan has expertise in molecular imaging, pre-clinical cancer imaging, cancer biology, nanotechnology, and molecular biotechnology.Dr. Massoud has expertise in molecular imaging, translational cancer imaging, neuro-oncology, and applications and perspectives relevant to clinical cancer management of glioblastoma patients. Read more

Oncology

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Cardio-Oncology: Management of Toxicities in the Era of Immunotherapy (Current Clinical Pathology) (2022) by Antonio Russo PDF

 

Ebook Info

  • Published: 2022
  • Number of pages: 136 pages
  • Format: PDF
  • File Size: 3.57 MB
  • Authors: Antonio Russo

Description

The development of immunotherapy in oncology field has revolutionized the prognosis of many types of cancer. The immune checkpoint inhibitors target receptors whose inhibition increases the activity of immune system cells against tumor cells. In recent years, new immunotherapies have been studied and approved in a growing number of tumors including melanoma, non-small cell lung cancer (NSCLC), and renal cell cancer (RCC). This volume provides a complete and updated state-of-art review regarding the management of cardiovascular toxicities from new immunotherapies. The manuscript is divided into different sections starting from the relationship between cancer and immune system to let the reader understand the new molecular concepts under immunotherapy development. Subsequent chapters describe specifically the immunotherapy options in solid tumor treatment and the main features of the immuno-related cardiovascular complications. This volume is written by experts in the oncological and cardiovascular fields and aims to provide to clinicians who approach current cancer patients a useful tool to move through the paths of modern cardio-oncology. An important section would afford the most relevant interventions needed to manage the cardiac events, suggesting how to reduce their impact and effects on oncological outcomes. The text concludes by addressing future perspectives in the cardio-immunology field, discussing many aspects such as the early detection of cardiovascular damage and the potential role of liquid biopsy in new damage-related biomarkers discovery.

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Editorial Reviews: From the Back Cover The development of immunotherapy in oncology field has revolutionized the prognosis of many types of cancer. The immune checkpoint inhibitors target receptors whose inhibition increases the activity of immune system cells against tumor cells. In recent years, new immunotherapies have been studied and approved in a growing number of tumors including melanoma, non-small cell lung cancer (NSCLC), and renal cell cancer (RCC). This volume provides a complete and updated state-of-art review regarding the management of cardiovascular toxicities from new immunotherapies. The manuscript is divided into different sections starting from the relationship between cancer and immune system to let the reader understand the new molecular concepts under immunotherapy development. Subsequent chapters describe specifically the immunotherapy options in solid tumor treatment and the main features of the immuno-related cardiovascular complications. This volume is written by experts in the oncological and cardiovascular fields and aims to provide to clinicians who approach current cancer patients a useful tool to move through the paths of modern cardio-oncology. An important section would afford the most relevant interventions needed to manage the cardiac events, suggesting how to reduce their impact and effects on oncological outcomes. The text concludes by addressing future perspectives in the cardio-immunology field, discussing many aspects such as the early detection of cardiovascular damage and the potential role of liquid biopsy in new damage-related biomarkers discovery. About the Author Antonio Russo, MDDepartment of Oncology – A.O.U.P. “P. Giaccone” University Hospital. Via del Vespro 129, CAP 90127 Palermo, Italy. Email: antonio.russo@usa.netNicola Maurea, MDDivision of Cardiology, Istituto Nazionale Tumori⁻IRCCS-Fondazione G.PascaleVia Mariano Semmola, 52 80131 Napoli, Italy. Email: nicolamaurea@virgilio.itDimitrios Farmakis, MD, PhD, FESC, FHFAAssoc. Professor, University of Cyprus Medical SchoolShacolas Educational Centre for Clinical Medicine, 215 Palaios dromos Lefkosias Lemesou, 2029, Nicosia, CyprusVisiting Professor, National and Kapodistrian University of Athens Medical SchoolAthens University Hospital Attikon, 1 Rimini St, 12462, Athens, GreeceEmail: farmakis.dimitrios@ucy.ac.cy; dimitrios_farmakis@yahoo.comAntonio Giordano, MDSbarro Institute for Cancer Research and Molecular Medicine and Center of BiotechnologyCollege of Science and Technology, Temple University200 Tuttleman Learning Center 1809 N 13th Street Philadelphia, 19122 USA. Email: giordano@temple.edu

Oncology

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An Insider’s Guide to Clinical Medicine 1st Edition (2019) by Archith Boloor PDF

 

Ebook Info

  • Published: 2019
  • Number of pages: 1771 pages
  • Format: PDF
  • File Size: 68.19 MB
  • Authors: Archith Boloor

Description

• Contains everything required for practical examination for medical students (both undergraduates and postgraduates).• Each of the chapter has been organized and described under the headings of case sheet format, diagnosis format, discussion on symptomatology, discussion on examination and summary of findings.• Comprehensive collection of all aspects of practical examination: Long Cases, Short Cases and Semi-long Cases; ECGs and X-rays; Instruments and Spotters; and Laboratory data interpretation.• Separate chapter on prerequisites for practical examination and common cases.• Exclusive sections for case sheet format, diagnosis format and system-wise summary of findings.• Annexures for last minute revision which include commonly asked definitions and grading systems with standard references.• Chapters on comprehensive geriatric assessment and approach to psychiatric illnesses.• All the clinical aspects have been thoroughly verified from standard textbooks and articles.• All the clinical examination skills have been described in a simple language with relevant illustrations.• For ease of understanding and revision, most of the points have been put in tabular format.

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Pathology

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