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Urothelial Carcinoma: Methods and Protocols (2018) (PDF) Wolfgang A. Schulz

  Basic Information: Year: 2018 Page Number: 362 File Type: PDF File Size: 8.34 MB Authors/ Editiors: Wolfgang A. Schulz Description: This volume details standard techniques for the characterization of urothelial carcinoma as well as methods to investigate mechanisms of carcinogenesis. Chapters guide readers on cellular and animal models for urothelial carcinoma and related diseases, molecular analyses from body fluids, and new approaches to therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily...

Traumatic and Ischemic Injury: Methods and Protocols (2018) (PDF) Binu Tharakan

  Basic Information: Year: 2018 Page Number: 245 File Type: PDF File Size: 6.37 MB Authors/ Editiors: Binu Tharakan Description: This volume focuses on procedures for the development and application of several research animal models and in vitro methods that allow researchers to gain insight into the underlying cellular, biochemical, and physiological mechanisms involved in traumatic and ischemic injury. The chapters in this book discuss topics, such as animal models and techniques commonly used to study traumatic brain injury, hemorrhagic shock, ischemic and hemorrhagic strokes, sepsis, burn injury, hind limb ischemia, myocardial-ischemia-reperfusion...

Preclinical MRI: Methods and Protocols (2018) (PDF) María Luisa García Martín

  Basic Information: Year: 2018 Page Number: 464 File Type: PDF File Size: 13.82 MB Authors/ Editiors: María Luisa García Martín Description: This volume discusses a variety of preclinical MRI methods and protocols to help technicians and researchers conduct studies in their respective fields. This book is organized into 7 parts: Part 1 covers the basics of MRI physics, relaxation, image contrast, and main acquisition sequences; Part 2 describes methodologies for diffusion, perfusion, and functional imaging; Part 3 looks at in vivo spectroscopy; Part 4 explores special MRI techniques that are less...

Preeclampsia Methods and Protocols (2018) (PDF) Padma Murthi

  Basic Information: Year: 2018 Page Number: 355 File Type: PDF File Size: 9.75 MB Authors/ Editiors: Padma Murthi Description: This volume presents the latest developments and techniques used to study the physiopathology, diagnosis, and treatment of pre-eclampsia. Written for clinicians, obstetricians, basic scientists, researchers, and students the chapters in this book provide methods to study placental function using in vitro and ex vivo model systems, comprehensive genetic analysis of pre-eclampsia, identifying critical angiogenic factors associated with the development of pre-eclampsia, and controlled experiments that investigate potential therapies. Written in the highly...

Membrane Protein Protocols: Expression, Purification, and Characterization (2003) (PDF) Barry S Selinsky

  Basic Information: Year: 2003 Page Number: 334 File Type: PDF File Size: 4.65 MB Authors/ Editiors: Barry S Selinsky Description: Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientation of amino acids in the active site of an enzyme demonstrates how substrate specificity is defined, and assists the medicinal chemist in the design of s- cific, tight-binding inhibitors. The shape and contour of a protein surface hints at its interaction with other proteins and with its environment. Structural ana-...
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