Clinical chorioamnionitis at term – definition, pathogenesis, microbiology, diagnosis, and treatment (2023) Eunjung Jung

Description

Expert review analyzing clinical chorioamnionitis, the most common infection-related diagnosis in labor and delivery. The content covers the definition (intrapartum fever plus signs of inflammation), pathogenesis (intraamniotic infection or sterile inflammation), key microbiology (Ureaplasma species), definitive diagnosis via amniotic fluid analysis (including microbial nucleic acid and IL-6/IL-8 levels), and standard treatment protocols (intrapartum antibiotics like ampicillin and gentamicin), noting the risks for both puerperal infection and neonatal complications, including cerebral palsy.