Reperfusion Changes After Stroke – Practical Approaches for Neuroprotection (2024) Jae H. Choi

Description

A review discussing the impact of early reperfusion therapy (thrombolysis and endovascular devices) for acute ischemic stroke. It details the phenomenon of reperfusion injury, caused by sustained or amplified ischemia-induced damages like hyperperfusion and blood-brain barrier disruption, and explores underlying mechanisms (excitotoxicity, inflammation). The text evaluates promising adjunct neuroprotective strategies, including selective brain hypothermia.