Syndromic and etiological classification predicts seizure freedom in childhood and youth onset epilepsy – A population-based study from the Norwegian Mother, Father, and Child Cohort Study (2025) Truls Vikin

Description

This population-based study determined the proportion of individuals with childhood and youth onset epilepsy who attain seizure freedom across seizure types, epilepsy types, etiologies, and syndromes using the latest International League Against Epilepsy (ILAE) classifications. Using data from the Norwegian Mother, Father, and Child Cohort Study (N=1044), researchers found that 78% achieved seizure freedom. Predictors of reduced likelihood of seizure freedom included early or adolescent onset, multiple seizure types, status epilepticus, developmental comorbidities, and abnormal neurologic findings.