Effect of endothelial responses on sepsis-associated organ dysfunction (2024) Miao Wu

Description

This review analyzes the crucial roles of endothelial responses during sepsis, including their effects on vascular permeability, inflammation, and thrombosis. It discusses how excessive endothelial activation leads to impaired microcirculation, tissue hypoperfusion, and sepsis-associated organ dysfunction, and summarizes current therapeutic interventions targeting these responses.