Rheumatology – Crystal Arthropathies and Gout (2024) Ameer Hamza

Description

This text focuses on rheumatological crystal arthropathies, primarily Gout. It details the metabolism of uric acid via de novo and salvage pathways, identifying both congenital (Lesch-Nyhan Syndrome) and acquired etiologies of hyperuricemia (e.g., renal failure, drug effects, and high cell turnover conditions). The book thoroughly explains the pathogenesis leading to acute arthritis caused by crystal deposition and immune response.