The urea‑to‑creatinine ratio – as an emerging biomarker in critical care a scoping review and meta‑analysis (2025) Michelle Carmen Paulus

Description

This scoping review and meta-analysis examines the Urea-to-Creatinine Ratio (UCR) as an emerging biomarker for severe protein catabolism and muscle wasting in critically ill patients. It investigates UCR’s association with mortality, length of ICU stay, and persistent critical illness, noting its potential clinical utility while addressing confounding factors like kidney dysfunction and hydration status.