Venous return and mean systemic filling pressure – Physiology and clinical applications (2022) Romain Persichini

Description

A narrative review focusing on the physiology of venous return, equal to cardiac output at steady state, and its determinants described by Guyton’s model: mean systemic filling pressure, right atrial pressure, and resistance to venous return. The review details current methods used to estimate these determinants at the bedside and explains their application in understanding the effects of common treatments (like fluid therapy and norepinephrine) in critically ill patients.