Oxidative Stress in Kidney Injury and Hypertension (2024) Willaim J. Arendshorst

Description

This review examines the critical role of oxidative stress, inflammation, and the renin–angiotensin–aldosterone system (RAAS) in causing kidney injury related to hypertension (HTN). HTN is a major contributor to chronic kidney disease (CKD) and end-stage renal disease (ESRD). The text discusses the influence of genetic and environmental factors, including the gut microbiome, and emphasizes that effective blood pressure management targeting these pathways is crucial for preventing renal damage and the progression of HTN-related CKD.