Plasma Cell Disorders – Diagnostic Approach and Management (2024) Unknown Author

Description

A detailed presentation outlining the diagnostic algorithm for plasma cell disorders, including initial workup (H&P, CBC, CMP, Skeletal Survey) and specialized testing (SPEP, UPEP, FLC ratio). It distinguishes between Monoclonal Gammopathy of Undetermined Significance (MGUS), Multiple Myeloma (MM), and Waldenström Macroglobulinemia (WM), detailing the role of CRAB criteria, bone marrow biopsy, and key prognostic factors (cytogenetics, B2-microglobulin). Treatment strategies for common complications, such as lytic lesions and infections, are also reviewed.