The convergent model of coagulation (2024) Jun Yong

Description

This article proposes a model of coagulation that converges with inflammation and innate immune activation as a unified response toward vascular injury, aiming to improve understanding beyond the conventional concepts of cascade and cell-based coagulation. It focuses on immunothrombosis and the role of damage-associated molecular patterns (DAMPs) to deliver novel diagnostics and therapeutics for challenges exposed by conditions like COVID-19 and vaccine-induced immune thrombotic thrombocytopenia.