Physiology of Pain Control Systems – Neurochemical and Descending Pathways of Analgesia (2024) Medical Physiology Core Curriculum

Description

A detailed study of pain control mechanisms, focusing on the Gate Control Theory and the intrinsic analgesic systems. Topics include the classification and action of Opioid peptides (Enkephalins, Endorphins, Dynorphins) and their receptors (Mu, Delta, Kappa), the components of the Supraspinal Analgesic System (Peri Aqueductal Grey area and Raphe Magnus Nucleus), and various treatment modalities for pain, including medical, electrical stimulation, and surgical interventions like cordotomy and prefrontal lobotomy.