Diabetes

This guideline provides recommendations for screening, diagnosis, and management of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in adults with prediabetes or type 2 diabetes (T2D). Key recommendations include using the Fibrosis-4 Index (FIB-4) score for risk stratification, emphasizing sustained weight reduction of at least 5% to 10%, and considering pioglitazone or subcutaneous semaglutide to improve glycemia and reduce liver fat content.

This diagnostic guide focuses on the technical aspects of diabetes testing, including the standardization and measurement procedures for key biomarkers such as HbA1c (glycated hemoglobin), glycated albumin, insulin, and C-peptide. It features contributions from recognized experts in clinical biochemistry and laboratory medicine.

A detailed analysis of the structure and function of the pancreas, focusing on the production and action of insulin and glucagon. The text differentiates between Type 1 and Type 2 Diabetes Mellitus (DM), explaining insulin resistance, beta-cell dysfunction and atrophy, and the development of acute complications like Hyperosmolar Hyperglycemic State (HHS) and osmotic diuresis.

A concise clinical guide presented in the popular 'Secrets' question-and-answer format, addressing top questions and essential information regarding the diagnosis and management of diabetes.