Endocrinology

An exciting contribution to the field, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvementis designed with two overriding objectives: to help readers understand the impact of vision impairment in people living daily with diabetes rather than considering diabetic retinopathy solely as a medical problem, and to explore what we know and don't know about the ways diabetes affect the eye. With the plethora of new information being generated, there are still a series of fundamental questions that must be addressed if effective treatments for diabetic retinopathy are to be found and applied. Developed by a renowned group of authorities, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvementoffers responses and context for a range of questions, such as: do metabolic factors beyond glucose contribute to vision-threatening diabetic retinopathy? If so, how do these lead to vision impairment? Is diabetic retinopathy a response to systemic metabolic abnormalities or are there unique ocular problems related to insulin resistance? What is the relationship between the neural, vascular, and inflammatory abnormalities in diabetic retinopathy? Do they represent a pathological cascade induced sequentially or simultaneous responses to one or more metabolic perturbations? The authors note that if we do not address these types of questions, it is possible that the long process of developing new therapeutics will target only one arm of the pathology and leave the retina open to damaging consequences of the others. State-of-the-art, comprehensive, and an invaluable addition the research and clinical literature, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers guidance and a significant step toward new scientific approaches that can lessen the devastating vision impairment associated with diabetes.

Count your carbs — and count on managing your diabetes Living with diabetes doesn't have to mean giving up all of your favorite foods. Carbs from healthy foods boost nutrition and supply essential fuel for your brain and body. Counting carbs is integral to managing diabetes because your carb choices, portion sizes, and meal timing directly impact blood glucose levels. Diabetes & Carb Counting For Dummies provides essential information on how to strike a balance between carb intake, exercise, and diabetes medications while making healthy food choices. — Covering the latest information on why carb counting is important for Type 1 diabetes, Type 2 diabetes, and gestational diabetes, this book provides the tools you need to best manage your diet and your diabetes. Nearly one in 11 people in the United States have diabetes and one out of every 3 adults have prediabetes (blood glucose levels above normal ranges). Diabetes rates are skyrocketing worldwide. If you or a loved one has been diagnosed — or is teetering on the edge of diagnosis — you'll find all the safe, trusted guidance you need to better manage your health through improving your nutrition and managing your carb intake. Discover how what you eat affects diabetes Explore the importance of carbs in nutrition and health Get the facts when it comes to fiber, fats, sweeteners, and alcohol. Decipher food labels and discover how to count carbs in bulk, fresh, and restaurant foods Manage your diabetes and reduce other diet-related health risks Improve blood glucose levels Sample meal plans in controlled carb count ranges Food composition lists for counting carbs and identifying best bet proteins and fats If you're one of the millions of people with diabetes or prediabetes in search of an accessible resource to help you portion and count carbs to better manage this disease, this is the go-to guide you'll turn to again and again because when it comes to diabetes — carbohydrates count.

The straight facts on treating diabetes successfully With diabetes now considered pandemic throughout the world, there have been enormous advances in the field. Now significantly revised and updated, this new edition of Diabetes For Dummies includes the latest information on diabetes medications and monitoring equipment, new findings about treating diabetes in the young and elderly, new ways to diagnose and treat long- and short-term complications, updated nutritional guidelines, new tools for measuring blood sugar and delivering insulin to the body, and much more. There's no question that the burden of diabetes is increasing globally: it's estimated that 387 million people worldwide are living with diabetes, and that staggering number is expected to increase an additional 205 million+ by 2035. If you or a loved one is part of this overwhelming statistic, you can take comfort in the sensitive and authoritative information provided in this hands-on guide. From monitoring and maintaining your glucose to understanding the importance of exercising and eating right—and everything in between—Diabetes For Dummies takes the guesswork out of living with diabetes and empowers you to take control and keep your life on a healthy track. Reduce your risk of diabetes complications Discover the latest and the tried-and-true options for monitoring blood sugar Get up to speed on the various diabetes medications and lifestyle strategies Improve diabetes control and overall health If you're one of the millions of diabetics or pre-diabetics in search of an accessible and up-to-date resource to help you manage this disease, Diabetes For Dummies is the trusted guide you'll turn to again and again.

Several major developments have occurred since the last edition of Handbook of Obesity: Clinical Applications, including new clinical trials, discoveries related to drug use, and greater understanding of the benefits of weight loss in obese patients. Now in its fourth edition, this volume continues to offer unparalleled depth and breadth of coverage concerning this global and chronic disease that affects and exacerbates associated conditions including diabetes and heart disease. The book is divided into five sections exploring essential factors involved in obesity prevention and treatment: Prevention of Obesity: Strategies such as reengineering the environment to encourage physical activity and prevent excessive weight gain in children and adults Evaluation of the Overweight or Obese Patient: Methods for assessing the overweight individual and the role of the primary care physician in patient management Medical Treatment of Obesity and Weight Management Issues in the Treatment of Obesity: Lifestyle for weight loss and weight maintenance, diet and exercise, medications, herbal agents, and issues related to childhood obesity Surgery: Screening for bariatric surgery, laparoscopic banding, liposuction, and other surgical techniques and strategies for operative and postoperative care Epilogue: The economic assessment and cost-effectiveness of treatments for obesity, how obesity is viewed internationally, and governmental responses to challenges arising from the growing prevalence of obesity Presenting the insight of international experts and edited by two eminent leaders in obesity research, the book is essential for health care providers in search of a comprehensive and up-to-date guide to treating obese patients.

In recent years, we’ve developed a much better grasp of the biological and other factors associated with the development of obesity. Reflecting our evolving understanding of causes and consequences,Handbook of Obesity: Epidemiology, Etiology, and Physiopathology provides comprehensive coverage of the biological, behavioral, and environmental determinants of this critical condition. This new edition is divided into five sections exploring essential factors involved in obesity research: History, Definitions, and Prevalence: Changes over time surrounding our notion of obesity, adiposity traits, and the epidemiology of obesity in various populations Biological Determinants of Obesity: Genetic and epigenetic evidence, fetal life and postnatal influences, the use of animal models in research, endocrine issues, molecular aspects, and issues related to viral infection and adiposityBehavioral Determinants of Obesity: The effects of food and ingestive behavior, smoking, breastfeeding, sleep duration, work/leisure time activity, and sedentary behaviorEnvironmental, Social, and Cultural Determinants of Obesity: The role of agriculture and the food industry, the urban environment, social and economic aspects, cultural factors, environmental pollutants, and economic costsConsequences of Obesity: How excess weight affects and exacerbates a range of comorbid conditions, including diabetes, cardiovascular disease, pulmonary disorders, arthritis, and cancerThis volume assembles the work of worldwide experts to deliver an up-to-date survey of the most essential information related to the causes of the obesity epidemic.

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When a patient is told that his prostate cancer has progressed to a new stage, he has both questions and concerns. Promoting Wellness Beyond Hormone Therapy, Second Edition, is written specifically to answer questions for patients whose prostate cancer is considered “hormone-refractory,” meaning that it no longer responds well to hormone therapy. The book provides a wealth of valuable resources for patients, caregivers, and healthcare professionals alike.• Comprehensive information on the many treatment options currently available• The latest updates on an exciting number of therapies undergoing testing now• Suggestions to patients to lessen or eliminate treatment side effects• “Question-and-Answer” format gives direct responses to patient queries• Health and wellness tips included throughout the bookArm yourself with a wealth of new information to discuss with your healthcare provider!

According to the United Nations, the number of people aged 60 years or over in the world is projected to be 1.4 billion in 2030 and 2.1 billion in 2050. Endocrinologists and other clinicians face the challenge of caring for the elderly. To do so, they need to incorporate geriatric principles into their clinical practice. Endocrinology of Aging: Clinical Aspects in Diagrams and Images presents chapters in a way that allows the reader to incorporate concepts and main facts of complex subjects in a visual way. As the global population becomes older, the need for a deeper understanding of geriatric pathology increases, and with it, the access to educational resources for the endocrinology and metabolism of aging. Chapters divided according to specific endocrine and metabolic systems, providing evidence-based content regarding what is known about the function of endocrine and metabolic systems altered during the aging process Addresses physiological changes that alter the pathophysiology of the clinical picture, explaining the characteristic pathological expressions of hormonal and metabolic disorders in the advanced age Editors and authors are clinical endocrinologists, geriatricians, internists and endocrine surgeons, with extensive global experience in clinical and experimental gerontology Considers the patient transitioning from young adult to elderly, discussing the endocrinological challenge to discern physiology from pathology Focuses on age as an essential factor for diagnostic and endocrine management Includes many pictures and diagrams, making it a user-friendly reference guide for practicing physicians

This book provides the most recent update on the management of neuroendocrine neoplasia (NEN), a term covering all tumors of various organs and/or with a particular histology, including MEN (multiple endocrine neoplasia) related tumors, MiNEN (mixed neuroendocrine-non-neuroendocrine neoplasms), NEC (neuroendocrine carcinoma) and Merkel’s carcinoma. NENs are heterogeneous in their biology, clinical presentation and prognosis, showing a great variability in aggressiveness and therapy response. As a result, their treatment is based on a large spectrum of options. The standard therapies are surgery in early disease, various loco-regional procedures in certain conditions and mostly of a palliative nature in metastatic disease. At present, thanks to our increased understanding of molecular signaling pathways, several pharmacological approaches can be used in patients with advanced NENs. Somatostatin analogs display both anti-tumor effects and symptom control. Novel peptide-radio-receptor treatment (PRRT) is used in patients with well differentiated tumors. The agents targeting angiogenesis and/or PI3K/AKT/mTOR pathway, alone or in combination with analogues, have provided encouraging results in advanced disease.

The primary gynecology text for over 25 years, Comprehensive Gynecology covers all of the key issues residents, specialists, primary care doctors, and other healthcare providers encounter in everyday practice. This 7th edition has been fully updated to include a wealth of new content, including current discussions of minimally invasive surgical approaches to gynecologic care, infertility issues and treatments, effectively managing menopausal patients, and more. Written in a clear, concise and evidence-based style, it offers the practical, in-depth coverage you need to remain at the forefront of your field.

Approximately 29 million Americans are diagnosed with Type 2 diabetes annually. Of that number, only about 36 percent (10.44 million diabetes sufferers) achieve satisfactory medical outcomes and would need additional help―rarely available―to reliably control their glucose levels. Contrary to popular belief, although anti-diabetic medications can lower sugar levels, nevertheless they have a poor performance track record because inflammation in the blood vessels persists.

The revised and updated fourth edition of Practical Endocrinology and Diabetes in Children offers a practical, highly clinical and up-to-date handbook of paediatric endocrinology and diabetes. The book is written in clear terms and offers a user-friendly format that is designed to be concise, yet comprehensive.. The international panel of expert contributors explore the range of endocrine disorders in children including growth, thyroid, adrenal and problems related to puberty.

Expertly bridging the gap between basic science and clinical information, Williams Textbook of Endocrinology, 14th Edition, brings together an outstanding collection of world-renowned authors to provide authoritative discussions of the full spectrum of adult and pediatric endocrine system disorders. New chapters and significant revisions throughout keep you up to date with recent advances in medications, therapies, clinical trials, and more. This essential reference is a must-have resource for endocrinologists, endocrine surgeons, gynecologists, internists, pediatricians, and other clinicians who need current, comprehensive coverage of this multifaceted field.

The goal of this book is not to follow a traditional systems or organ-based approach but rather to encourage our readers to think of the patients as complex biochemical systems. The book provides information that supplements the more traditional approaches and provides a detailed overview of the metabolic knowledge needed for surgical practice. The text reviews normal physiology, the pathophysiology of starvation and surgical stressors. It also focuses on appropriate nutritional repletion for various common disease states. Specifically, chapters address the severe metabolic demands created by systemic inflammation, infection, and major insults such as trauma and burns. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information. As biochemical aspects of modern medicine are advancing rapidly, chapters have been updated and several new chapters have been added in order to help readers keep pace in this race for state-of-the-art knowledge.

The ADA Standards of Medical Care in Diabetes is a key resource for healthcare professionals involved in diabetes care, education, and support. One of the most important pieces of literature to read prior to becoming a Diabetes Care and Education Specialist and for clinical practice, the Standards of Care book is a study must!

This book provides a comprehensive guide for nurses practicing in any area of endocrinology and at any level of expertise. Endocrinology Nursing is a fast-developing specialty with nurses performing advanced roles and expanding their practice to run independent nurse-led services. Supported by the European Society of Endocrinology (ESE) and edited by members of the ESE Nurses Working Group, this is the first book ever published specifically for endocrine nurses. It is also an excellent resource for endocrinology specialty trainees, general practitioners, medical and nursing students, expert patients and nurses working in specialties such as fertility, osteoporosis, oncology, obesity, urology and gynaecology, who look after patients with endocrine-related disorders.

It is well-established, through extensive peer-reviewed published research, that physical activity and exercise training can impact the reproductive endocrine system of women. This ground-breaking, comprehensive title presents a range of unique insights into the opposite question: how the reproductive endocrine system of women affects their exercise ability. More precisely, the thematic question explored in this work is: if exercise affects reproductive hormones, conversely then could the reproductive hormones have physiological effects unrelated to reproduction that influence the capacity of women to exercise? In exploring this question, the goal is to better understand the unique physiology of women and whether female sex hormones might account for some of the variance in physiological performance between amenorrheic and eumenorrheic women, and within women across the age span as they experience menarche to menopause. Sex Hormones, Exercise and Women: Scientific and Clinical Aspects synthesizes the research by exploring the physiology and psychology behind these occurrences. This novel title will not only be of interest to researchers, exercise scientists, graduate students, and clinicians; it will also serve as a source of valuable information for female athletes and their trainers in the context of preparing for competitions.

This unique book will serve as a valuable resource for clinicians and researchers interested in prolactin physiology and pathophysiology and those who are involved in the care of patients with related disorders, including hyperprolactinemia and prolactin-secreting pituitary adenomas. Timely and up-to-date, it opens with a review of the historical aspects of prolactin research and a discussion of pituitary anatomy and physiology. Several chapters examine basic and translational aspects of prolactin physiology, focusing on recent developments and future directions. The main portion of the book is comprised of chapters presenting the clinical aspects of prolactin excess or deficiency, with particular emphasis placed on prolactin-secreting pituitary adenomas and co-secreting tumors. Concluding chapters address prolactin-secreting pituitary adenomas in special populations – women in the preconception period or during pregnancy, children and adolescents, and men – as well as plurihormonal and aggressive adenomas and carcinomas.

Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism.

An ideal resource for both pediatricians and endocrinologists, Sperling’s Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today’s clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice. Whether you’re preparing for certification or have extensive clinical experience, this detailed, authoritative reference helps you increase your knowledge and determine the best possible course for every patient.

The paediatric endocrinologist deals not only with common problems involving growth, puberty, and diabetes, but also with specific hormonal defects involving glands such as the thyroid, parathyroid, adrenals, and pituitary. These can vary from common variants of normals which will be encountered by all doctors dealing with children, to more rare disorders requiring specialist input.

Providing clinicians with the latest developments in research, this new edition of Type 1 Diabetes is a succinct and practical guide to the diagnosis, evaluation, and management of Type 1 diabetes. Part of the Oxford Diabetes Library series, this pocketbook contains 12 fully updated chapters on key topics such as history, epidemiology, aetiology, presentation, insulin treatment, and microvascular and macrovascular complications. It also features new chapters on technology, diet and lifestyle, and pregnancy planning to ensure the reader is fully equipped with the latest understanding of Type 1 diabetes.

Nutritional Pathophysiology of Obesity and Its Comorbidities: A Case-Study Approach challenges students and practitioners to understand the role of nutrients within the pathophysiology and development of disease, specifically those diseases which develop as a result of obesity. Through a case-based approach, the author presents complex clinical scenarios that require multiple treatment strategies, including targeted diet modification as an adjuvant to medical therapy.

This concise, case-based text discusses the current state of the art for the diagnosis and management of metabolic bones diseases. Each chapter opens with a unique case presentation and utilizes a consistent format that includes relevant anatomy, physiology, and pathophysiology as well as examination, treatment approaches and clinical outcomes. Topics covered include osteoporosis, rickets and osteomalacia, hypoparathyroidism and pseudohypoparathyroidism, osteogenesis imperfecta, Paget's disease of bone, calcium and phosphorous disorders, hypophosphatasia, sclerotic bone disorders, fibrous and osteochondroplasia, and other malignancies of bone.

Thyroid Surgery: Principles and Practice will bridge a gap between the huge platform of literature available about thyroid surgery and the practical working reality. The pearls in techniques and surgical procedures are exhaustively detailed with authors' individual experience enriched with quality photographs. This book covers management of large/massive multinodular goiters which are the hallmark of Indian thyroids. However, the emphasis will be more on applying this knowledge to a given patient and would largely revolve around this theme. It aims to provide a take-home message in controversial areas and is a ready reference to all interested in learning the science and craftsmanship of thyroid surgery.