This textbook provides a detailed, modern, and concept-based approach to the fundamental principles of genetics, emphasizing problem-solving and critical thinking skills essential for students in biology, medicine, and related fields.
A collection of reproducible research protocols and methodologies focused on comparative genomics. Each volume in the Methods in Molecular Biology series provides step-by-step protocols, including introductory overviews, materials lists, detailed procedures, and helpful notes with troubleshooting advice.
Rare monogenic disorders of the primary cilium (ciliopathies) are characterized by extreme presentations of common diseases, such as diabetes, hepatic fibrosis, and kidney failure. This study investigates the contribution of common genetic variants within Mendelian ciliopathy genes to common complex diseases pathogenesis. Researchers performed association studies of 16,874 common genetic variants across 122 ciliary genes with 12 quantitative laboratory traits in 452,593 individuals in the UK Biobank, identifying 101 statistically significant associations. The findings challenge the widely held belief that the cilium is an organelle important mainly in rare syndromic disease pathogenesis, demonstrating the utility of a Mendelian pathway-based approach to genomic association studies.
This book focuses on the genetic improvement of small millets, addressing their historical importance in Asian and African diets, analyzing the factors contributing to their decline, and discussing the need for technological breakthroughs in yield and improved value chains compared to major cereals like rice and wheat.
A comprehensive review analyzing the role and application of epigenetics in driving modern advancements and improvements within agricultural crop science.
This volume examines behavioral genetics research on temperament and personality across the lifespan. The contributors explore nuanced questions that move beyond simple heritability estimates to address issues regarding genetic and environmental mechanisms or processes associated with the development of temperament, personality, and related outcomes.
A comprehensive review book covering the essential topics in Pathology and Genetics, designed for medical students and practitioners preparing for exams.
A study conducting genome-wide selection analysis and machine learning feasibility tests using Deep Neural Network Genomic Prediction (DNNGP) on a large panel of 2,430 modern maize inbred lines. The research explores rare and favorable allelic variations to understand missing genetic diversity and improve future breeding strategies for traits like yield potential, density tolerance, and disease resistance.
An analysis of Fibromyalgia (FMS) and Myofascial Pain Syndrome, centered on the hypothesis of central sensitization. This work reviews historical definitions, current diagnostic criteria (ACR 1990), societal costs, differential diagnoses for widespread pain, and the relationship between FMS and psychiatric co-morbidity.
A detailed analysis of antianginal drugs, covering the definition and types of Angina Pectoris, determinants of myocardial O2 demand, and the pharmacology and classification of therapeutic agents including Nitrates, Beta Blockers, and Calcium Channel Blockers. Objectives include recognizing variables contributing to myocardial supply versus demand and detailing drug usage for acute attacks versus chronic prophylaxis.
Ebook Info
Published: 2008
Number of pages: 512 pages
Format: PDF
File Size: 10.71 MB
Authors: Mortimer M. Civan
Description
Current Topics in Membranes provides a...
Ebook Info
Published: 2015
Number of pages: 260 pages
Format: PDF
File Size: 15.33 MB
Authors: M. Soledad Cortina
Description
This book covers the field of...
A comprehensive resource utilizing the clinical Q&A Secrets format, covering the essential knowledge and current practices for the diagnosis and management of hypertension.
A comprehensive question and answer self-study resource designed for physicians assessing or reinforcing their knowledge for the ABIM Certification or Maintenance of Certification (MOC) Board exam. Content covers numerous subspecialties including Gastroenterology, Cardiology, Nephrology, Endocrinology, Hematology, Oncology, and Rheumatology. Up to 75 AMA PRA Category 1 Credits™ are available.
A comprehensive guide detailing the principles and techniques used in osteopathic manipulative treatment (OMT) specifically targeting the assessment and resolution of visceral dysfunction, emphasizing manual methods for improving organ motility and function.
Ebook Info
Published:
Number of pages:
Format: PDF
File Size: 6.53 MB
Authors: Erwin Loh
Description
Resident Readiness: Emergency Medicine prepares you for success...
This book provides expertise and practical guidance for Emergency Department physicians and nurses to increase competencies for diagnosing and treating common mental health conditions. It focuses on managing acute behavioral emergencies, implementing innovative models of care, and applying tactics, tools, and techniques from both evidence-based medicine and Lean service operations to improve patient care, flow, and safety.
This book addresses complex and often overlooked management issues within Neuroanesthesia and Neurocritical Care. It emphasizes the necessity of maintaining the brain in an adequately working state during critical illness, covering topics related to traumatic brain injury (TBI), stroke, and subarachnoid hemorrhage (SAH) that are frequently neglected in general intensive care practice.
