This systematic review summarizes evidence on antibiotic pharmacokinetic alterations caused by obesity and provides guidance for dose adjustment in adult patients (BMI >30 kg/m²). The review found that obesity modestly alters the pharmacokinetics of β-lactam antibiotics (not supporting routine dose adjustments), but significantly impacts aminoglycosides and glycopeptides, for which weight-based dosing is recommended. Overall evidence certainty was low or very low.
This text provides clinical information, including adult and pediatric dosages, administration guidelines, and indications for various antibiotics. It covers aminopenicillins (Amoxicillin, Ampicillin) and their combinations (e.g., Augmentin, Unasyn), detailing bioavailability and dosing schedules. Furthermore, it classifies and provides detailed drug profiles for the first, second, and third generations of cephalosporins, listing specific agents (e.g., Cefadroxil, Cephalexin, Ceftriaxone) and their uses in treating conditions like UTIs, RTIs, and otitis media.
Ebook Info
Published: 2020
Number of pages: 258 pages
Format: PDF
File Size: 17.75 MB
Authors: Tejinder Singh
Description
The edition has been revised with some...
A comprehensive guide covering the essential techniques, equipment selection, lighting setup, and clinical protocols necessary for high-quality image capture and documentation in modern dental practice.
Ebook Info
Published:
Number of pages:
Format: PDF
File Size: 11.21 MB
Authors: Roger A. Mackinnon
Description
Transradial Access: Techniques for Diagnostic Angiography and...
A comprehensive textbook covering the core science, advanced science, and clinical practice of endodontics, including diagnosis, radiographic interpretation, pain control, cleaning and shaping, obturation, surgical procedures, regenerative endodontics, and management of traumatic injuries and emergencies.
Ebook Info
Published:
Number of pages: 202
Format: PDF
File Size: 24,11 MB
Authors: Oculus
Description
This guide is intended to assist Pentacam®/Pentacam® HR/ Pentacam®...
This book provides a lucid and thought-provoking approach to performing 'good research,' covering the methods, aims, and limitations of science. It discusses measurement, data collection, design of experiments, hypothesis testing, and the ethics of science, offering valuable advice on writing up findings suitable for publication, especially for graduate students in the natural sciences.
Ebook Info
Published:
Number of pages:
Format: PDF
File Size: 8.89 MB
Authors: Michael F. Murphy
Description
A new global focus, new editorial team,...
A foundational and comprehensive textbook covering the core principles and clinical practice of pediatric medicine, including neonatology, infectious diseases, and organ systems.
The primary aim of this book is to assemble data needed by clinicians in their daily decision making in pediatric urology. It is focused on pivotal clinical questions, providing a synopsis of the evidence for diagnosis and treatment of conditions.
Ebook Info
Published:
Number of pages:
Format: PDF
File Size: 22.89 MB
Authors: Lichtenstein, Daniel A.
Description
Chronic leg ulcers affect approximalety 1% of...
This book is an advanced text focusing on the intricate details of guided bone regeneration (GBR) for vertical and horizontal ridge augmentation. Described as an atlas and 'show-and-tell,' it presents complex surgical procedures in a step-by-step format, complete with extensive imagery, drawings, radiographs, and 'Lessons learned' sections to emphasize critical learning objectives in hard and soft tissue reconstruction.
This handbook offers a comprehensive and up-to-date review of cancer immunology and immunotherapy, emphasizing key findings and clinically relevant data regarding the interactions between the immune system and cancerous cells, epigenetic changes, and the development of combinatorial immunotherapeutic strategies to combat cancer.
