This systematic review summarizes evidence on antibiotic pharmacokinetic alterations caused by obesity and provides guidance for dose adjustment in adult patients (BMI >30 kg/m²). The review found that obesity modestly alters the pharmacokinetics of β-lactam antibiotics (not supporting routine dose adjustments), but significantly impacts aminoglycosides and glycopeptides, for which weight-based dosing is recommended. Overall evidence certainty was low or very low.
This text provides clinical information, including adult and pediatric dosages, administration guidelines, and indications for various antibiotics. It covers aminopenicillins (Amoxicillin, Ampicillin) and their combinations (e.g., Augmentin, Unasyn), detailing bioavailability and dosing schedules. Furthermore, it classifies and provides detailed drug profiles for the first, second, and third generations of cephalosporins, listing specific agents (e.g., Cefadroxil, Cephalexin, Ceftriaxone) and their uses in treating conditions like UTIs, RTIs, and otitis media.
Ebook Info
Published:
Number of pages:
Format: PDF
File Size: 72.78 MB
Authors: Jacquelyn G. Black
Description
Neurosurgery Primary Examination Review: High Yield Questions,...
A comprehensive medical reference focusing on the prevention and management of complications arising during or after cancer therapy. It addresses the increasing complexity of patient care related to treatment side effects and comorbidities.
A comprehensive guide detailing the evidence-based clinical practice of laparo-endoscopic hernia repair, featuring contributions from multiple international experts.
This book explores the relationship between oxidative stress and disorders affecting the cornea and lens. It examines findings from applied basic research and clinical practice, potentially covering topics such as point-of-care testing and antioxidant supplementation in vision-related medical disorders.
Detailed introductory notes covering the fundamental physical principles of the electrocardiogram, including galvanometer operation, cardiac depolarization and repolarization, AV node conduction dynamics, and the generation of key electrical vectors (atrial and ventricular).
This Handbook presents established and innovative perspectives on involving older adults as co-creators in ageing research. It reorients research and policy toward more inclusive and adequate designs that capture the voices and needs of older adults. It introduces participatory approaches, highlights key methodological aspects, gives insights from cross-cultural projects, and examines issues when involving older participants at each step of the research process.
A comprehensive textbook covering fundamental concepts, diagnostic tools, and contemporary treatment modalities in the field of clinical orthodontics, emphasizing biomechanical principles and modern appliance systems.
A comprehensive handbook for professionals detailing the theory and practice of clinical gait analysis. Topics covered include basic and advanced measurement techniques, the conventional gait model, electromyography (EMG), clinical video analysis, physical examination, quality assurance, interpretation, and practical instructions for setting up and maintaining a gait analysis service and laboratory.
This up-to-date revision guide for the MRCP SCE (Specialty Certificate Examination) in neurology covers the core areas essential for exam success. The chapters are structured to align with the exam syllabus and help candidates learn and recall core concepts. Content is carefully curated, encompassing all areas tested, and utilizes bullet points, tables, and color illustrations. A particular strength is the inclusion of neuroradiology and neuropathology, which account for a significant section of exam questions.
Ebook Info
Published: 2014
Number of pages: 131 pages
Format: PDF
File Size: 3.7 MB
Authors: Aniz Girach
Description
This clinically oriented book is the first...
A detailed analysis of the mechanical properties of bone and the methods used for testing the bond and stress characteristics at the bone-implant interface. Key topics include biomechanics, material testing, and orthopedic implants.
