This systematic review summarizes evidence on antibiotic pharmacokinetic alterations caused by obesity and provides guidance for dose adjustment in adult patients (BMI >30 kg/m²). The review found that obesity modestly alters the pharmacokinetics of β-lactam antibiotics (not supporting routine dose adjustments), but significantly impacts aminoglycosides and glycopeptides, for which weight-based dosing is recommended. Overall evidence certainty was low or very low.
This text provides clinical information, including adult and pediatric dosages, administration guidelines, and indications for various antibiotics. It covers aminopenicillins (Amoxicillin, Ampicillin) and their combinations (e.g., Augmentin, Unasyn), detailing bioavailability and dosing schedules. Furthermore, it classifies and provides detailed drug profiles for the first, second, and third generations of cephalosporins, listing specific agents (e.g., Cefadroxil, Cephalexin, Ceftriaxone) and their uses in treating conditions like UTIs, RTIs, and otitis media.
Ebook Info
Published: 2015
Number of pages:
Format: PDF
File Size: 2.81 MB
Authors: La Flamme, Anne C., Orian, Jacqueline Monique
Description
Over the past...
A comprehensive anatomy textbook specifically written for dental students, aimed at covering the necessary anatomical knowledge required for the field and reflecting modern dental education curricula.
A compilation of key excerpts intended for healthcare professionals and consumers, covering evidence-based information on the benefits of food in preventing and treating diseases. Topics include the Mediterranean Diet, Vitamin D in Metabolic Syndrome, Nutrition and Mental Health, and the relationship between diet and conditions such as acne.
A comprehensive guide providing clinical pathways and evidence-based approaches for diagnosis and treatment in the specialized field of Neuro-Ophthalmology.
A textbook focusing on the essential principles and practices of pharmacy services within hospital and clinical environments, covering topics such as drug management, clinical therapeutics, dispensing procedures, and patient counseling.
This review summarizes available data regarding the use of tracheostomy in Intensive Care Unit (ICU) patients requiring prolonged mechanical ventilation or suffering loss of airway protection. It discusses the advantages (facilitated weaning, reduced sedation, improved mobilization) and risks (mortality, complications like tracheal stenosis), emphasizing that a personalized, step-by-step approach is crucial for determining the optimal timing and technique, recommending the percutaneous single dilator technique under fibroscopic guidance when training is adequate.
Ebook Info
Published: 2017
Number of pages:
Format: PDF
File Size: 38.52 MB
Authors: Singh, Hariqbal, M.D. and Sheik, Parvez, M.D.
Description
This book is...
A practical medical text providing tips and techniques for the clinical diagnosis and bedside approach to heart disease, intended for physicians and cardiologists.
Ebook Info
Published: 2010
Number of pages: 172 pages
Format: PDF
File Size: 4.07 MB
Authors: Bernd Kirchhof
Description
Unlike the cornea or lens, the retina...
Standardized physical growth charts for Egyptian girls aged 2 to 21 years, detailing reference percentiles for height, weight, and BMI. The document includes instructions for proper anthropometric measurements (weight, head circumference, supine length, and standing height) and BMI calculation, based on a study sample of over 13,800 girls.
A detailed procedural manual covering both cosmetic and reconstructive techniques within facial plastic surgery. It includes step-by-step guidance on complex surgical interventions, anatomy, and pre- and post-operative patient care, serving as a primary resource for residents and practicing surgeons.
