This systematic review summarizes evidence on antibiotic pharmacokinetic alterations caused by obesity and provides guidance for dose adjustment in adult patients (BMI >30 kg/m²). The review found that obesity modestly alters the pharmacokinetics of β-lactam antibiotics (not supporting routine dose adjustments), but significantly impacts aminoglycosides and glycopeptides, for which weight-based dosing is recommended. Overall evidence certainty was low or very low.
This text provides clinical information, including adult and pediatric dosages, administration guidelines, and indications for various antibiotics. It covers aminopenicillins (Amoxicillin, Ampicillin) and their combinations (e.g., Augmentin, Unasyn), detailing bioavailability and dosing schedules. Furthermore, it classifies and provides detailed drug profiles for the first, second, and third generations of cephalosporins, listing specific agents (e.g., Cefadroxil, Cephalexin, Ceftriaxone) and their uses in treating conditions like UTIs, RTIs, and otitis media.
Ebook Info
Published: 2010
Number of pages: 532 pages
Format: PDF
File Size: 98.28 MB
Authors: Johannes W. Rohen
Description
This Color Atlas of Anatomy features...
A comprehensive policy and clinical guide focused on respiratory health and conditions in infants, children, adolescents, and young adults, developed by the American Academy of Pediatrics (AAP) Section on Pediatric Pulmonology and Sleep Medicine.
Ebook Info
Published: 2020
Number of pages: 1170 pages
Format: PDF
File Size: 197.6 MB
Authors: Linda D. Boyd
Description
Each new print copy includes Navigate...
Ebook Info
Published: 2023
Number of pages: 848 pages
Format: PDF
File Size: 304.19 MB
Authors: Geoffrey C Gurtner MD FACS
Description
Comprehensive and fully up...
Evidence-based report intended for healthcare providers and policy-makers detailing the strategy for asthma management and prevention based on current best evidence and medical knowledge and practice.
Ebook Info
Published: 2018
Number of pages: 289 pages
Format: PDF
File Size: 27.07 MB
Authors: Lyne Racette
Description
New.
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Ebook Info
Published:
Number of pages:
Format: PDF
File Size: 6.13 MB
Authors: Julie C. Lumeng
Description
Written by internationally renowned experts, the 3rd...
A comprehensive textbook focusing specifically on reconstructive and aesthetic procedures related to the hand, as part of the multi-volume third edition series on Plastic Surgery.
Guidelines and therapeutic strategies focusing on immune modulation and anti-inflammatory therapy for ocular disorders, based on the IOIS recommendations.
A comprehensive collection of challenging and common clinical case histories, designed to aid trainees and practitioners in neurosurgery with the diagnosis, investigation, and management of various neurological conditions.
A detailed guide focusing on the role of clinical nutrition, dietary interventions, and lifestyle factors in the management of Attention-Deficit/Hyperactivity Disorder (ADHD), covering its neurobiological basis, prevalence, and practical counseling tools for caregivers.
