This systematic review summarizes evidence on antibiotic pharmacokinetic alterations caused by obesity and provides guidance for dose adjustment in adult patients (BMI >30 kg/m²). The review found that obesity modestly alters the pharmacokinetics of β-lactam antibiotics (not supporting routine dose adjustments), but significantly impacts aminoglycosides and glycopeptides, for which weight-based dosing is recommended. Overall evidence certainty was low or very low.
This text provides clinical information, including adult and pediatric dosages, administration guidelines, and indications for various antibiotics. It covers aminopenicillins (Amoxicillin, Ampicillin) and their combinations (e.g., Augmentin, Unasyn), detailing bioavailability and dosing schedules. Furthermore, it classifies and provides detailed drug profiles for the first, second, and third generations of cephalosporins, listing specific agents (e.g., Cefadroxil, Cephalexin, Ceftriaxone) and their uses in treating conditions like UTIs, RTIs, and otitis media.
A volume in the Essentials in Ophthalmology series that provides an update on the progress and clinically relevant achievements regarding the cornea and external eye diseases, including corneal allotransplantation, allergic disease, and trachoma.
This updated pictorial atlas focuses on endocrine and metabolic disorders, providing multiple illustrations and thorough discussions on diagnosis, management, and treatment plans using updated guidelines. It comprehensively discusses the latest therapies, including diabetes technology, and presents a large number of clinical images (thyroid ultrasounds, DXA images, bone scans). It includes new chapters on transgender medicine and obesity, making it a valuable resource for endocrinologists, clinicians, residents, fellows, and trainees.
This analysis covers the basic anatomy and physiology of the visual system, detailing the three layers and contents of the eye. Key topics include the physics of light, calculation of refractive power (diopters), refractive index (RI), and the mechanisms of light striking a surface. It also comprehensively covers the protective mechanisms of the eye (tear film, eyelid reflexes, and blinking) and provides an in-depth examination of the formation, circulation, composition, and functions of the Aqueous Humor and the Cornea.
This review addresses the presentation, diagnosis, and management of congenital choanal atresia (CA) and choanal stenosis (CS) in neonates. It differentiates between life-threatening bilateral CA, which presents with respiratory distress and requires immediate surgical correction, and unilateral CA/CS, which can often be managed medically or present later in life. The article emphasizes distinguishing CA/CS from other causes of congenital nasal obstruction.
Ebook Info
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File Size: 21.53 MB
Authors: Jacques S. Abramowicz
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Since the third edition of Grieve's Modern...
Ebook Info
Published: 2010
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Format: PDF
File Size: 131.32 MB
Authors: Prof. Walter R. Frontera MD PhD
Description
Thoroughly updated and now...
Comprehensive review covering the definition, pathophysiology (ion channel defects and channelopathies), clinical manifestations, specific differences (hypo- vs hyperkalemic types), and management strategies for periodic paralysis, a group of primary disorders causing episodic muscle weakness.
A foundational textbook offering detailed coverage of microscopic morphology, diagnostic criteria, and clinical correlation for common and rare cutaneous diseases. This second edition includes expanded chapters on molecular diagnostics and challenging melanocytic lesions.
A comprehensive global resource providing statistics and analysis on the prevalence, incidence, mortality, and economic impact of diabetes worldwide. The 10th edition includes detailed chapters on diagnostic criteria, methods, regional distribution, youth-onset diabetes, and the relationship between COVID-19 and diabetes.
A comprehensive collection of multiple-choice questions (MCQs) designed for pediatric exams, covering core clinical topics, causes of under-5 mortality, neonatology, and critical decision-making regarding ethical issues such as Do Not Attempt Resuscitation (DNAR) status and resource allocation in pediatric intensive care units.
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File Size: 109.43 MB
Authors: Lawrence R. Goodman
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Forming part of the best selling and...
