Pediatric Oncology

A review of acute myeloid leukemia (AML) in children and adolescents. The topic covers the clinical presentation, evaluation (including laboratory tests and bone marrow examination), and the context of improved survival rates compared to ALL/LBL.

This series provides up-to-date information on important topics in pediatric oncology, covering the entire spectrum of clinical management, including diagnosis, treatment, radiation oncology, supportive care, and survivorship, aiming to equip readers with the latest knowledge relevant to daily practice.

This book presents international experience in the diagnosis of pediatric tumors, focusing on small volume biopsy techniques. It details the use of fine-needle aspiration and core needle biopsy, integrating cytology, histology, and molecular investigation with clinical and radiological information.

A comprehensive textbook dedicated to the excellence in research, scholarship, and education concerning the diagnosis and clinical management of cancer in children.

Analyzes the role of genetic risk factors and germline pathogenic variants in the etiology of childhood cancers. It discusses the current limitations and findings of genome-wide sequencing efforts (which attribute about 15% of cases to germline variants) and explores evolving technologies investigating non-coding regions and emerging mechanisms.

A comprehensive review of immunotherapy strategies, including monoclonal antibodies, stem cell transplantation, and methods for overcoming immune suppression, used in the treatment of pediatric cancers and hematological malignancies.

A comprehensive textbook detailing the principles and clinical application of radiation therapy for pediatric patients with cancer and other relevant conditions.

This book addresses the growing group of long-term childhood cancer survivors, focusing on the late effects and chronic diseases they develop as a consequence of their cancer and treatment. It emphasizes that about 80% of children survive cancer, but a large proportion will suffer from varied late effects, necessitating critical long-term follow-up and individualized care plans based on risk profiles.

This book provides a modern and comprehensive analysis of retinoblastoma, detailing its historical context (e.g., the two-hit hypothesis), the role of the retinoblastoma pathway in cancer development, and modern treatment modalities. It emphasizes the multidisciplinary approach necessary for ocular salvage, assessment of visual outcomes, and the development of new targeted therapies for this challenging malignancy.

This chapter analyzes the epidemiology of cancer in children and adolescents (patients under 20 years), detailing incidence rates, relative survival improvements (up to 85.1%), and the continued role of malignant neoplasms as a leading cause of disease-related mortality in this age group. It contrasts pediatric malignancies, dominated by lymphohematopoietic and CNS cancers, with typical adult epithelial tumors.

This foundational textbook provides detailed, evidence-based coverage of the biology, diagnosis, and treatment of malignant diseases in children. It includes updated protocols for chemotherapy, radiation therapy, surgical intervention, and long-term survivorship management.

A guideline and pocket guide for drug therapy and chemotherapy protocols in neonates and infants (under 1 year old). It assists physicians and healthcare professionals by detailing drug metabolism, excretion, toxicity, dose adjustments, and safe treatment practices based on the patient's specific age (week or month).