An introduction to the principles of toxicology, defining concepts like toxin, poison, and venom, discussing the dose-response relationship (Paracelsus), lethal dose (LD50), and various types of poisoning (acute, subacute, chronic).
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File Size: 3.7 MB
Authors: Anika Niambi Al-Shura
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Immunology has emerged as a key component...
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Published: 2020
Number of pages: 314 pages
Format: PDF
File Size: 19.89 MB
Authors: Shahrokh C. Bagheri
Description
This book offers up-to-date guidance in...
Clinical guidance on evaluating for ectopic pregnancy. The absence of a definitive intrauterine pregnancy visualized on ultrasound should be considered an indicator of ectopic pregnancy until proven otherwise. Discusses the significance of visualizing free fluid around the uterus or in the right upper quadrant in cases of ruptured ectopic pregnancy.
A high-yield revision resource presented in a question-and-answer format, covering core clinical topics in Otorhinolaryngology (ENT). Focuses on scenario-based learning, differential diagnoses (e.g., Meniere's disease), and appropriate management strategies for conditions like vertigo and tonsillitis, commonly tested in medical licensing examinations.
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File Size: 15.95 MB
Authors: Carlos Navarro Vila
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This volume provides a comprehensive, state-of-the art...
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File Size: 5.57 MB
Authors: John Rees
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Gale Encyclopedia Of Prescription Drugs, a two-volume set...
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File Size: 3.31 MB
Authors: Empar Lurbe
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Medical students encounter many challenges on their path...
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File Size: 18.78 MB
Authors: Anil Agarwal
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A trusted textbook for undergraduate students for more...
Rare monogenic disorders of the primary cilium (ciliopathies) are characterized by extreme presentations of common diseases, such as diabetes, hepatic fibrosis, and kidney failure. This study investigates the contribution of common genetic variants within Mendelian ciliopathy genes to common complex diseases pathogenesis. Researchers performed association studies of 16,874 common genetic variants across 122 ciliary genes with 12 quantitative laboratory traits in 452,593 individuals in the UK Biobank, identifying 101 statistically significant associations. The findings challenge the widely held belief that the cilium is an organelle important mainly in rare syndromic disease pathogenesis, demonstrating the utility of a Mendelian pathway-based approach to genomic association studies.
