This article reviews the effects of chronic opioid use on the gastrointestinal tract, noting that opioids disrupt intestinal permeability through pathologic m-opioid receptor and Toll-like receptor signaling, leading to issues beyond standard opioid-induced constipation (OIC). The authors discuss the use of peripherally active m-opioid receptor antagonists, such as methylnaltrexone, which are effective for OIC and also help to ameliorate the opioid-induced disruption of intestinal permeability.
Ebook Info
Published:
Number of pages:
Format: PDF
File Size: 15.48 MB
Authors: Harold Ellis
Description
Data interpretation questions based on clinical cases are...
A case-based textbook presenting real-world patient scenarios (like involuntary movements, headache, and visual/speech disturbances) to guide readers through diagnostic reasoning, differential diagnoses, and therapeutic management in the field of Neurology.
A comprehensive, step-by-step instructional guide detailing the modern techniques and procedures involved in Minimally Invasive Glaucoma Surgery (MIGS).
A guide for professionals engaged in biomedical research and clinical work on the process of writing and publishing scientific articles, focusing on effective communication strategies.
Ebook Info
Published: 2013
Number of pages: 499 pages
Format: PDF
File Size: 30.86 MB
Authors: M.D. Basak, Samar K.
Description
New edition bringing ophthalmologists up...
A clinical handbook providing essential reference information and normal ranges for various immunological markers, including serum immunoglobulins, complement components, antibacterial antibodies, specific IgE grades, and lymphocyte subsets.
A comprehensive guide detailing the diagnostic procedures and therapeutic management strategies for disorders affecting the visual pathways and ocular motor system.
A comprehensive clinical guide focused on the etiology, pathology, and current treatment strategies for conditions affecting the ocular surface, including dry eye syndrome, infectious keratitis, chemical burns, and surgical reconstruction techniques.
A comprehensive visual atlas focused on the diagnosis, management, and internal medicine aspects of diabetic foot syndrome and its related complications.
Ebook Info
Published:
Number of pages:
Format: PDF
File Size: 15.44 MB
Authors: Sarah E. Nelson
Description
New topics in this edition include professionalism...
A detailed guide on Blood Flow Restriction (BFR) training, covering its history, the mechanisms of hypertrophy (metabolic stress, hypoxia, cellular swelling, hormonal factors), safety data and contraindications, methods for calculating appropriate pressure levels, and practical guides for applying BFR during strength and aerobic exercise to maximize muscle mass and strength gains.
