Diabetes and Metabolic Dysfunctioneassociated Steatotic Liver Disease in Adults – A Clinical Practice Guideline (2025) James Kim

Description

This guideline provides recommendations for screening, diagnosis, and management of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in adults with prediabetes or type 2 diabetes (T2D). Key recommendations include using the Fibrosis-4 Index (FIB-4) score for risk stratification, emphasizing sustained weight reduction of at least 5% to 10%, and considering pioglitazone or subcutaneous semaglutide to improve glycemia and reduce liver fat content.